Most athletes would agree that lactic acid build-up in the muscles is the bane of all long-distance runners – but not American jogger Dean Karnazes. The 53-year-old has a rare genetic condition that rapidly flushes lactic acid from his system, allowing him to run indefinitely without ever experiencing a cramp or a seized muscle. The extreme runner has completed a marathon to the South Pole at -25C, and completed 50 back to back marathons in 50 days. He’s also jogged a whopping 350 miles in just 80 hours and 44 minutes, without any sleep!

When people exercise, glucose is converted into energy and a by-product of this reaction is lactic acid. As it builds up in the muscles, it causes cramps and fatigue, and signals the brain to stop. But in Dean’s case, he never receives those signals because lactic acid never builds up in his muscles. So he’s able to run for long distances over very long periods of time, giving him an edge in some of the toughest endurance competitions in the world.

“At a certain level of intensity, I do feel like I can go a long way without tiring,” Dean said, speaking to The Guardian. “No matter how hard I push, my muscles never seize up. That’s kind of a nice thing if I plan to run a long way. To be honest, what eventually happens is that I get sleepy. I’ve run through three nights without sleep and the third night of sleepless running was a bit psychotic. I actually experienced bouts of ‘sleep running’, where I was falling asleep while in motion, and I just willed myself to keep going.”

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For most people, running one or two full marathons a year is quite the feat,  but for 33-year-old Rob Young it’s merely a short warm-up. This British superhuman did the unthinkable last year, completing a whopping 370 marathons, which basically means he ran more than one marathon per day!

It all started as a silly bet with his partner Joanna Hanasz on a Sunday morning, in April 2014, as they watched the TV coverage of the London Marathon. It was, in fact, Young who had insisted that he’d rather stay in and watch TV than go for a walk in the park with their son. He obviously wasn’t very interested in running at the time, and actually considered it ‘boring’.

But something changed that morning, when Hanasz teased him that he couldn’t run marathons, even if he tried. Young jokingly replied that he would bet her ‘twenty pence’ that he could run 50, a challenge that he later took seriously. The very next morning he woke up at 3.30 am, printed out the route of the Richmond Marathon, and completed it before work. And he felt so good that he returned to it every day, running the equivalent of 10 marathons by the end of the week.

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Meet Derek Mitchell, an inspiring 35-year-old race runner who weighs a whopping 545 pounds. Despite his heavy frame, he’s spent the past year walking and running a total of 21 5k races and two 10k events. He even made it halfway through a muddy, 10-mile obstacle course!

Mitchell, a Kansas City native, was diagnosed with a noncancerous tumor on his pituitary gland five years ago, a condition that slows down his metabolism and is the primary cause for his obesity. Although he was put on medication to shrink the tumor, Mitchell felt that “at one point, I was using that condition as a crutch, telling myself, ‘I’ll wait for the pills to start working before I start working out or change my eating habits.’”

But he realised that wasn’t a very good plan in November 2014, when his body weight reached an all-time high of 625 pounds. “That’s when I knew I needed to make a change, and decided to start with a new year’s resolution.” So in the beginning of 2015, he cut soda from his diet, switched to more nutritious food options, and tried switching to a healthier lifestyle.

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American student Barclay Oudersluys is making headlines for attempting a 100-day coast-to-coast run, inspired by the movie Forrest Gump. He set off on the epic journey on Saturday, from California’s Santa Monica Yacht Harbor and Pier, and he plans to reach Marshall Point Lighthouse in Maine at the end of 100 days. That’s a total of 3,200 miles, with 32 miles to cover per day.

Barclay is calling his attempt ‘Project Gump’, as it was inspired by the protagonist of the 1994 film Forrest Gump. Although the route covered by Tom Hanks’s character isn’t completely revealed in the movie, Barclay has managed to chart a course quite similar to it, by studying contextual clues.

“I don’t really know what made me want to do it,” he said. “Forrest Gump is my favorite movie. And so when I decided to do this run, I looked up the two points where he had gone to and decided then.” The course he’s charted will take him through California, Nevada, Arizona, New Mexico, Colorado, Kansas, Missouri, Illinois, Indiana, Ohio, Pennsylvania, New York, Vermont, New Hampshire and Maine.

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Tony ‘the fridge’ Phoenix-Morrison got his name from his unique way of running marathons – with a fridge strapped to his back. Yes, a real refrigerator. Why on earth would anyone want to do that, you ask? Well, for Tony, this is a way to gain people’s attention so he can raise money for charity.

“My friends knew I was an ultra-runner, so trying to raise money by just running the Great North Run wasn’t getting me anywhere,” said the 49-year-old marketing manager from South Tyneside, in the UK. “So I thought about something different. I wanted an extreme challenge, something that would push me to my limits. In 2011, I told everyone I was running with a fridge and the world went mad for it! I ended up on the news in 17 different countries over night.”

Contrary to expectations, Tony isn’t really trying to show off his strength by running with the 42 kg Smeg Fridge. “I hate the fridge,” he insisted. “It starts off tough, then gets impossible. I don’t put it on for show. I should never have ran with the fridge because I was injured when I began. I went running with kettle bells in a rucksack and it swung everywhere, damaging my lower back.” According to Tony, there is no other way to prepare for the physically grueling marathon than by being mentally strong.

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Most people forget their New Year resolutions within a few weeks, some can’t even make it a day. But a Melbourne couple in their 60s have completed what they set out to do, every day of last year. For the whole of 2013, Janette Murray-Wakelin, 64, and Alan Murray, 68, ran marathons every single day across Australia. They completed their 366^th marathon on January 1, running 44 kilometers down the Yarra Trail to their home at Warrandyte. The couple ran a total of 15,000 kilometers last year.

The Murrays wanted to set a positive example of being responsible for one’s own health. “We wanted to share as much, with as many people, for as long as we could, a really positive message of hope and just to show people anything is possible if you put your mind to it and set a goal to achieve,” said Janette.

Janette and Alan followed a strictly vegan diet for the whole year, to help them achieve their goal. At 4 a.m., they would eat 10 bananas, a grapefruit and a date smoothie, before hitting the road. At 8 a.m. they had 10 more bananas, and a green smoothie at 9 a.m. Once they hit 31 kilometers, they would stop to snack on a fruit salad. At the 37-kilometer mark they would have three oranges. They would finish running by 4 p.m. and settle down to a scrumptious dinner of an avocado, vegetable juice and salad.

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Kim Allen, a 47-year-old ultra-distance runner from New Zealand, recently broke the world record for running the longest distance without sleep. She surpassed the previous record of 486 km (set by American Pam Reed in 2005) by running a whopping 500 km. It took her 86 hours, 11 minutes and 9 seconds of non-stop running to complete the challenge.

Kim began at 6 am on the 19th of December, in Auckland, and kept at it for four long days. She ran initially, but slowed down to a walk in the final laps. The mother-of-four called her achievement “Sleepless in Auckland.” “It’s all a bit surreal at the moment,” she said, shortly after completing the feat.

This wasn’t her first attempt; Kim tried to beat Reed’s record last year, but she could only manage 370 km before she had to stop. This time, she reached her goal with blistered feet and swollen ankles. But Kim was so ecstatic about her achievement that she referred to her state as “just a bit weary.” She also said that she was overwhelmed and could not believe her quest was over.

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29-year-old Kenichi Ito, from Tokyo, says he has loved monkeys ever since he was a child. He has always been able to identify with animals, and harbored an ambition to adopt one of their traits. His deep desire has been fulfilled, now that he is actually able to move around quite comfortably on all fours, just like a monkey. It all started one day when he witnessed a monkey running quickly. From that point on, he claims he practiced running like the animal every day, until he became the fastest man on all fours.

“You know, my face and body kind of look like a monkey, so from a young age everybody used to tease me, saying ‘monkey, monkey,'” Ito said in his neat apartment, sitting in front of a large poster of a chimpanzee. But I wasn’t really bothered because I really liked them, and somewhere inside of me I had this ambition to adopt one of their traits. When I saw a monkey that could run fast, I knew I’d found it – and from that point on I practiced running like a monkey every day,” Keinichi Ito says about how it all started.

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If you’re a runner, you probably already know about the issue of nipple bleeding, but for people like me, who only run when they’re being chased, this is new.

I stumbled across this set of photos on Unknown Highway, one of  my favorite sites, and thought I’d investigate further to find out what exactly makes men’s nipples bleed during marathons. After a bit of reading I learned not to ever run for miles, dressed in a cotton shirt.

Apparently, cotton and sweat just don’t make a good team. After you run a few miles, you start to sweat a lot and the cotton absorbs the sweat and gets heavier and heavier. That’s when it starts to act like sandpaper against your sensitive nipples. So, if you want to run in a marathon make sure you’re wearing something made out of light-weight material, like a CoolMax t-shirt.

If you don’t have anything else but cotton t-shirts, run shirtless. It’s better for people to see your belly wiggling that to see your nipples bleeding, trust me. Also, I know this sounds a bit kinky, but you might want to rub a bit of Vaseline or other lubricant on your nipples, before a race.