A 27-year-old man dubbed the “unluckiest man alive” suffers from a rare disease that causes him to experience flu-like symptoms whenever he orgasms.

The unnamed man’s case was recently reported in the medical journal Urology Case Reports by a team of doctors who successfully managed to treat the condition with antihistamine. Scientists described the man’s rare illness as an allergic, or autoimmune, response to his own sperm, which caused flu-like symptoms like fever, a cough, sneezing, muscle weakness, as well as concentration, memory, and even speech issues. Because of these debilitating symptoms associated with his own orgasm, the man had actively been avoiding sleeping with his girlfriend for a long time.

As bizarre as the case described above may sound, it is certainly not unique. Scientists have so far uncovered almost 60 cases of people affected by this rare and serious condition known as Post-Orgasmic Illness Syndrome (POIS). In fact, it is increasingly being recognized as a debilitating cause of sexual dysfunction in males, but because it’s so rare and unusual, it is often misdiagnosed.

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Can you imagine looking in the mirror and not recognizing the person staring back at you. That’s what Lena, a 29-year-old Russian woman suffering from prosopagnosia, a rare condition that makes it impossible to recognize faces, including her own.

Lena Ash only learned that she was suffering from prosopagnosia last year. Before that, she had always tried to convince herself that she wasn’t simply slower than other people. Even as a child, Lena had problems recognizing faces, and talking to her parents about it didn’t really help. She doesn’t blame them for it, as they didn’t even know such a condition existed, and it’s not like they could simply google her symptoms back then. Not even the neurologists she went to for her headaches, migraines, low blood pressure and nausea could figure out the cause of her health problems, and this all made her feel ashamed of herself.

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A recently-published study detailed the bizarre case of an Italian woman who grew eyelash-like hairs inside of her mouth multiple times.

The unnamed woman reportedly visited doctors about her condition over a decade ago, when she was just 19-years-old. She visited doctors and complained of hair growing out of her gums, which had only been documented a handful of times in medical literature. Testing revealed that the young woman also had ovarian cysts, and she was later diagnosed with polycystic ovary syndrome (PCOS), a relatively common hormonal disorder. Women suffering from PCOS tend to produce more testosterone than normal, of which a condition called hiruitism – increased growth of hair on the body – is a known side effect.

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Body Integrity Identity Disorder (BIID) is a serious psychological condition that gives able-bodied people a strong desire to be disabled. It’s what made this woman from North Carolina purposely blind herself by dropping drain cleaner into her eyes!

Jewel Shuping, 30, revealed that she’s been obsessed with blindness since childhood. “My mother would find me walking in the halls at night, when I was three or four years old,” she said. “By the time I was six, I remember that thinking about being blind made me feel comfortable.” So she would spend hours staring at the sun, hoping that it would damage her eyes.

The obsession increased as she aged, and by the time she was a teenager, Jewel had taught herself to move around in thick black sunglasses. She got her first cane at age 18 and became fully fluent in braille by age 20. “I was blind-swimming, which is pretending to be blind, but the idea kept coming up in my head and by the time I was 21 it was a non-stop alarm that was going off,” she said. Read More »

Physical changes during puberty are completely normal, but in Salinas, a remote village in the southwestern Dominican Republic, they are downright extreme. For some of the boys living here puberty is the time they actually grow a penis. Many of the children are born without male genitalia and are raised as girls, but they eventually become men in their teenage years. The phenomenon is so familiar to the people of Salinas that the children – called ‘guevedoces’ (penis at 12) – are not considered abnormal at all.

The condition is apparently the result of a rare genetic disorder that occurs due to a missing enzyme. This prevents the production of dihydro-testosterone – a type of male hormone – when the baby is in the womb. All fetuses have internal glands called gonads and a small bump between their legs called tubercle. At around eight weeks, the enzyme 5-α-reductase triggers a huge surge of dihydro-testosterone in male fetuses, converting the tubercle into a penis. In female fetuses, the tubercle becomes a clitoris. But in many babies born to Salinas women, the enzyme is missing entirely.

So these babies are born with the tubercle intact and no testes, and are often mistaken for female babies. It isn’t until they reach puberty that another surge of testosterone is produced, which is when the male reproductive organs are formed. As their voices deepen, their penises begin to emerge as well.

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Although he’s only 30, Yuan Taiping from Chongqing in southwest China, looks like an 80-year-old man. He suffers from a bizarre medical condition that’s caused his skin to age prematurely. He’s visited numerous doctors, but no one has been able to find him a cure so far.

Yuan, who works as a manager at a construction company, looked normal until the age of 20. But then he noticed changes on his face and body – he developed oedemas on his arms and legs and deep lines on his face. At first he thought it was due to stress, but when wrinkles appeared on his forehead, he realised that something wasn’t right. So he decided to get medical help, but in spite of visiting countless hospitals and taking lots of medication in the past decade, nothing has worked.

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Laura Ponce, a nursery school teacher in Lins, Brazil, suffers from a strange condition that causes her to cry ‘crystal’ tears. The white plaques start off as soft blobs inside her eyes, but they harden when she blinks in an attempt to expel them, finally emerging as solid white crystals.

This happens to her for weeks at a time, with a new plaque forming as soon as she expels another. It gets so bad at times that she has to take time off work, to remove as many as 30 plaque membranes from her eye in a day. “A clot starts to swell then I have to open my eye to take out the membrane,” she explained. “When it dries it hardens, it gets really hard, it hurts a lot.”

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People often use the phrase “I feel you pain” when trying to comfort somebody, but usually it has a figurative meaning. That’s not the case with Joel Salinas, a doctor suffering from a rare condition called mirror-touch synesthesia which actually allows him to feel the physical pain of his patients.

Salinas, a neurologist at Massachusetts General Hospital, says that he has had the condition since childhood. Whenever he would observe other people hugging, for instance, he would feel hugged as well. And when he saw people get hit, he felt the discomfort too. “When I see people, I have the sensation of whatever touches their body on my own body, and it’s kind of reflected as a mirror,” he explained.

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Since 2009, 32-year-old Shanyna Isom has been suffering from a mysterious skin condition that causes fingernails to grow out of the hair follicles all over her body. The mystery illness is so inconceivably strange that even after five years, doctors have no idea what is wrong with her. According to physicians treating her at the Johns Hopkins Medical Center, in Baltimore, Shanyna is the only person in the world suffering from the bizarre disease.

It all started in 2009, when Shanyna – then a law student at the University of Memphis – suffered a massive asthma attack. She went into the emergency room where was given a large dose of steroids. Soon after, she developed an allergic reaction to the steroids, and her skin began to itch uncontrollably. Although she was prescribed Benadryl and other allergy drugs , her condition kept getting worse.

“It was uncontrollable and we didn’t know what it was. Black scabs were coming out of her skin,” Shanyna’s mother Kathy Gary explained. “The nails would grow so long and come out and regrow themselves. They are hard to touch and stick to you.” Soon, her legs started to turn black.

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One of the world’s strangest and rarest mental disorders is Cotard’s Syndrome. Also known as the Cotard Delusion, the Nihilistic Delusion, and the Walking Corpse Syndrome, CS causes sufferers to believe that they are dead (figuratively or literally) and do not exist.

I always thought the walking dead only existed in movies and video games. Until I read about Cotard’s Syndrome (CS), that is. Apparently, people who suffer from this rare but very real mental disorder actually believe that they have died and are not of this world anymore. The condition is named after a 19^th century French neurologist, Jules Cotard. In 1880, he presented the first patient to be diagnosed with the condition at a lecture, calling her Mademoiselle X. She is said to have suffered from significant self-loathing, a denial of the existence of God, the Devil, and several parts of her own body. She also believed she was damned for eternity and incapable of dying a natural death, so she had no reason to eat anymore. Mademoiselle X eventually starved to death.

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Bojana Danilovic, a young woman from Serbia, suffers from a strange condition that has left both doctors and scientists baffled. The 28-year economics graduate sees everything upside down.

Experts from Harvard University and at the Massachusetts Institute of Technology who examined Bojana Danilovic say she suffers from a rare brain condition called ‘spatial orientation phenomenon’. In layman’s terms that means her eyes see things the right way, but for some reason her brain changes them. Although there have been some similar cases recorded in history, Bojana’s case is truly unique. Everything in her life has been backwards, even the way she came into this world – feet first. Her parents remember that when she first started crawling, she would always move backwards, and when she began to walk, she did it in reverse. The remarkable young woman says her mother had to take a leave from her job in order to teach her to walk like all the other children. It took a lot of practice, but she finally managed to walk forward. Only this was only the beginning of a very unusual life.

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Haemolacria is a real physical condition that causes people to actually cry tears of blood. The tears of people suffering from this condition may range from being just tinged red, to entirely made of blood. While the exact cause or cure for this condition is not clear, it is known to be a symptom of several blood-related diseases or tumors. Let’s take a look at the three most talked-about cases of haemolacria in recent years: Read More »

I suppose it could be worse, but 47-year-old David Harding has become the first man in Britain (and probably the world) who has undergone therapy to cure his addiction to sausages.

David has had at least one sausage a day ever since he was five years old – either in sandwiches, as fry-ups or main meals – and often eats as many as 13 of them. He spends around $1,150 on sausages every year, and has even bought a deep chest fridge just so he could store his favorite treats – McWhinney’s Irish pork sausages.

Last year, David realized he could be a sausage addict, when his wife Susan decided to cook something different for dinner, and he didn’t get his usual fix. He acted a little crazy in that particular situation which made him realize something was wrong, so he decided to seek professional help. So far, Harding has forked out $3,100 on four sessions with a professional therapist and two with a therapist, buts says he’s as far from curing his strange addiction as he was when he first started counseling.

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Wu Yuanbi, a 53-year-old woman, from Chongqing, China, has recently performed surgery on herself, with a common kitchen knife.

Wu, who works as a migrant worker, has been suffering from a chronic condition known as Budd-Chiari syndrome, for the last 13 years. This causes her stomach to gradually fill up with large quantities of fluid, rendering her unable to work and making id difficult to perform even the most simple tasks. Back in 2002, Wu and her family used all their life savings to pay for a medical procedure in which doctors removed 25 liters of fluid from her belly. Unfortunately, a relapse of the condition followed, and the woman found herself in need of a second surgery. However, she and her family were too poor to pay the 50,000 yuan ($7,686) fee, so Wu Yuanbi was forced to do something truly shocking.

One day, after her husband, Cao Yunhui, left for work, the woman slit her stomach open with a kitchen knife, desperate to relieve the pressure that had built up inside. She had to endure excruciating pain for several hours, until her husband came home and found her lying in a pool of yellow fluid and intestines. She was immediately rushed to the hospital with a 10 cm-long cut across her stomach, and saved by the medical staff. Wu later said “If I had passed away, I would have at least spared my family the trouble of looking after me.”

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For the last three years, doctors have been trying to figure out what makes Twinkle Dwivedi‘s body ooze blood through her eyes, feet and even her head, but she remains a medical mystery.

When Twinkle’s case first appeared in the international media, many hurried to call her a fake, but after countless tests and procedures, including blood transfusions, doctors are still baffled by her strange bleeding. A group of medical specialists, led by dr. George Buchanan, recently traveled to North India to investigate the 14-year-old Twinkle, but all they have been able to say was that “she really suffers from a condition we have never seen before.”

The young teen remembers her disorder first appeared when she was just 11, and her classmates started mocking her and calling her disgusting. Although her bleeding didn’t hurt at all, she felt scared and alone, because no one would come near her. At first she would cry when she saw her clothes soaked with blood, but now she just keeps quiet, and prays she will eventually get better.

Despite her parents efforts, who took her to see the best doctors, Twinkle Dwivedi still bleeds from her eyes and pores, up to 14 times a day. Read More »